Recombinant Human TSLP
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PODS® Growth Factors
The product is currently not available as PODS®, please check back in the future.Description
Thymic Stromal Lymphopoietin (TSLP) is a hematopoietic cytokine produced in several tissues including the heart, liver and prostate. TSLP induces the release of T-cell attracting chemokines from monocytes and regulates the maturation of myeloid and epidermal dendritic cells. TSLP signals through a heterodimeric receptor complex containing the TSLP receptor (TSLP-R/CRLF2) and IL-7R α chain.Activity Assay
Human TSLP is fully biologically active when compared to standard. The activity is determined by the induced proliferation of BaF3 cells transiently expressing human IL-17Rα and human TSLP-R and it is typically 0.05 - 0.3 ng/ml. There is no data currently available.AA Sequence
MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLLK QQAlternative Names
Thymic Stromal LymphopoietinProduct Details | |
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Length | 132 aa |
Molecular Weight | 15.1 kDa |
Structure | Monomer |
Source | E. coli |
Accession Number | Q969D9 |
Purity | ≥95% determined by reducing and non-reducing SDS-PAGE |
Endotoxin Level | ≤1.00 EU/μg as measured by kinetic LAL |
Formulation | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5 |
Reconstitution | Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions. |
Stability and Storage |
12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed. |