LY294002
LY294002
Activity
LY294002 shows a highly selective inhibitor of PI3K in-vivo. LY294002 can transfer cells to specific inhibition of PI3K, inhibition of PI3K/Akt signaling pathways, including inhibition of common Akt phosphorylation.
Effect
LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.
Alternative Names
LY 294002, LY-294002
2-Morpholin-4-yl-8-phenylchromen-4-one, 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
References
1. Gharbi, SI., et al. 2007. Biochem J. 404(1): 15-21. PMID: 17302559
| Product Details | |
|---|---|
| Formula | C19H17NO3 |
| Molecular Weight | 307.34 |
| CAS Number | 154447-36-6 |
| Purity | >99% |
| Solubility | DMSO, ethanol |
| Stability and Storage | Stable at -20°C. Keep away from direct sunlight. |
