Exosomes are 40 - 150 nm diameter microvesicles that form within the cell. Exosomes contain and protect various RNA and protein cargos which are secreted into the blood and other bodily fluids. Exosomes are taken up by nearby and distant cells where their cargo can profoundly influence cellular activity. Consequently, there is interest in the potential of exosomes as vectors for gene therapy, and diagnostics which can detect disease based on analysis of exosomes recovered from blood, urine, saliva and other body fluids.
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