0 items$0.00

PODS PeptiGels

Manchester BIOGEL and Cell Guidance Systems have collaborated to produce PODS-PeptiGels kits which combine the benefits of two existing innovative cell culture technologies - synthetic peptide hydrogels (PeptiGels®) and sustained release growth factors (PODS®) - to provide a reproducible and highly controlled environment for 3D cell culture.

These ready-to-use kits allow researchers to tailor the cell culture system to suit their individual cell types by selecting specific growth factors and peptide hydrogel combinations for a truly relevant in vitro system.

PODS-PeptiGels have a wide range of applications in:

  • In vitro cultures
  • Bioprinting
  • Disease modeling
  • Regenerative medicine
  • Drug discovery
  • Biomanufacturing
  • High throughput screening

 Get in touch at info@cellgs.com for more information or to request a quote.

PODS-PeptiGels Applications

PODS® Growth Factors:

PODS® are cubic crystals made from 100% protein that slowly release their protein cargo through nanopores. This enables researchers to better control the behaviour of cells in hydrogels. The sustained release of proteins provided by PODS® crystals generates stable growth factor concentrations enabling precise control of the cell culture environment, significantly improving the health and quality of cells.

PODS® Controls (Empty, GFP and mCherry)

  • PODS® Empty - These crystals are composed solely of polyhedrin protein. Therefore, these PODS® crystals do not contain any cargo protein and are intended to be used as negative controls alongside cargo-containing PODS® co-crystals.
  • PODS® GFP and mCherry - PODS® GFP and mCherry behave in the same way as other PODS® co-crystals but do not contain a bioactive cargo protein. Rather they have fluorescent proteins that enable visualization and localization of PODS® crystals in PeptiGels utilizing fluorescence microscopy. In addition, PODS® GFP and mCherry can be used in a similar way to PODS® Empty as a non-bioactive control.

For full PODS® product listing, please click here.

PeptiGels®:

PeptiGels® are ready-to-use, fully synthetic, biologically relevant peptide hydrogels that are formulated to meet your specific cell culture needs.

PeptiGels® are designed with a range of mechanical properties and biochemical functionalities to closely mimic the native cellular micro-environment to allow the growth of a wide range of cell types. PeptiGels® come in a variety of elasticities (stiffnesses) and can be functionalised with peptide sequences including collagen (GFOGER), fibronectin (RGD), & laminin (IKVAV & YIGSR).

 

Choosing your PeptiGels®

PeptiGels®

Charge

Biomimetic Functionality

Compatible Cells 

Alpha 4

+2 None

Most suitable for the general culture of a wide variety of cell types

Alpha 4 Plus

+2

RGD & GFOGER

Most suitable for the general culture of a wide variety of cell types
Alpha 2 +1 None Most suitable for the culture of neuronal and other related cells

Alpha 2 Plus

+1 RGD Most suitable for the culture of neuronal and other related cells
Alpha 1 Neutral None Most suitable for the culture of chondrocytes and nucleus pulposes
Gamma 4 Plus +2 RGD & GFOGER Most suitable for the culture of spheroids and organoids
Bespoke Gels Varied RGD, GFOGER, IKVAV & YIGSR Tailored to match your cell type

 

Ordering your PODS-PeptiGels kit:

Once you have chosen your tailored PODS-PeptiGels combination email order@cellgs.com to request a quote. As with conventional growth factors PODS work best within a defined range. We recommend PODS-PeptiGels are used within the following range of ratios:
  

 

 Guide for the appropriate number of PODS® per ml of PeptiGel®.

 

If you are unsure on which combination of PODS® and PeptiGels® to use or would like to request any other PODS® growth factor, please get in touch and we'd be more than happy to help! 

Products

PODS Empty 50 Million PeptiGel $518.00
PODS GFP 50 Million PeptiGel $518.00
PODS GFP 250 Million PeptiGel $791.00
PODS GFP 1 Billion PeptiGel $1,767.00
PODS mCherry 50 Million PeptiGel $518.00
PODS mCherry 250 Million PeptiGel $791.00
PODS mCherry 1 Billion PeptiGel $1,767.00
PODS Human Activin A 50 Million PeptiGel $518.00
PODS Human Activin A 250 Million PeptiGel $791.00
PODS Human Activin A 1 Billion PeptiGel $1,767.00
PODS Mouse Activin A 50 Million PeptiGel $518.00
PODS Mouse Activin A 250 Million PeptiGel $791.00
PODS Mouse Activin A 1 Billion PeptiGel $1,767.00
PODS Rat Activin A 50 Million PeptiGel $518.00
PODS Rat Activin A 250 Million PeptiGel $791.00
PODS Rat Activin A 1 Billion PeptiGel $1,767.00
PODS Human Activin B 50 Million PeptiGel $518.00
PODS Human Activin B 250 Million PeptiGel $791.00
PODS Human Activin B 1 Billion PeptiGel $1,767.00
PODS Human BDNF 50 Million PeptiGel $518.00
PODS Human BDNF 250 Million PeptiGel $791.00
PODS Human BDNF 1 Billion PeptiGel $1,767.00
PODS Human BMP-2 50 Million PeptiGel $518.00
PODS Human BMP-2 250 Million PeptiGel $791.00
PODS Human BMP-2 1 Billion PeptiGel $1,767.00
1