leading the way
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SINEUP™ allows up to 10-fold increases in expression levels of target proteins by increasing the efficiency of translation. It has been proposed that the mechanism is similar to IRES elements which increase the efficiency of translation initiation. Transcription of the target gene is unaltered. Similar to RNAi, which can be used to knockdown (down-regulate) protein levels, SINEUP™ technology does not rely on the direct manipulation of the target gene.


SINEUP £775.00