Recombinant Mouse CNTF
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DescriptionCiliary Neurotrophic Factor (CNTF) is a neurotrophic factor that promotes the survival of neuronal cell populations, neurite outgrowth, and neurotransmitter synthesis. CNTF also plays an important protective role during nervous system injury.
Activity AssayMouse CNTF is fully biologically active when compared to standard. The activity is determined by the induced proliferation of TF-1 cells and it is typically less than 50 ng/ml. This corresponds to an expected specific activity of 2.0 x 104 units/mg.
AA SequenceMAFAEQSPLT LHRRDLCSRS IWLARKIRSD LTALMESYVK HQGLNKNISL DSVDGVPVAS TDRWSEMTEA ERLQENLQAY RTFQGMLTKL LEDQRVHFTP TEGDFHQAIH TLTLQVSAFA YQLEELMALL EQKVPEKEAD GMPVTIGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRVIS SHHMGISAHE SHYGAKQM
Alternative NamesCiliary Neurotrophic Factor
|Molecular Weight||22.6 kDa|
|Purity||≥95% determined by reducing and non-reducing SDS-PAGE|
|Endotoxin Level||≤1.00 EU/μg as measured by kinetic LAL|
|Formulation||In solution on 10 mM sodium phosphate, 150 mM sodium chloride, 10 mM DTT, 50% Glycerol, pH 7.5 at a concentration of 0.5 mg/ml for 5 and 20 μg vials and 1.4 mg/ml for larger size vials|
|Stability and Storage||12 months from date of receipt when stored at -20°C as supplied.|