A deadly arms race takes place between cancer cells and our immune system. A recent study published in Nature shows the importance of monocytes in the development of a healthy anti-cancer immune response, how cancer blocks monocyte activity and how this can be restored.
Tumours evade immune surveillance through mechanisms that impair immune responses, allowing the tumour to grow and spread without being eliminated by the immune system. Understanding the interplay between cancer and immune cells is allowing the development of new therapies.
Calorie restriction (CR) has long been recognized to increase both health span (the duration of a healthy life) and lifespan, but is difficult to adhere to. Recently published papers indicate that a dietary supplement (also produced by some gut microbes) can achieve the same effect.
Viral vectors, such as AAV, are used for the delivery of RNA and DNA therapeutics. Machine learning, a type of AI, is enabling the rapid iterative development and improvement of these therapeutic vectors.
Pressure regulation, valves, and balanced distribution: A domestic heating system and the human circulatory system share a remarkably wide range of similarities.
Karyotyping remains an important assay when working with any animal cell. Here we discuss the benefits and limitations.
Tropical climates yield high levels of biodiversity. So perhaps it is not surprising that the natural resources of many tropical islands have made significant contributions to the development of some very big (and some not so big) name drugs.
The genomic instability of iPSCs is well documented. What is the impact of these genetic alterations on downstream applications and what can we do to mitigate their impact?
Scientific fraud, while not extremely common, is a significant concern within the scientific community. Does the lack of reproducibility point to a greater problem?
Within our bodies, microbes have developed an essential, commensal role and are found in many niches. A comprehensive study, recently published in Cell, provides a fascinating insight into the role of microbes in cancer and how they can modulate prognosis and responses to treatment.
