Recombinant Human RELM-β

Code Description Price Qty
GFH160-5 Recombinant Human RELM-β, 5 μg £44.21
GFH160-25 Recombinant Human RELM-β, 25 μg £105.00
GFH160-100 Recombinant Human RELM-β, 100 μg £262.50
GFH160-500 Recombinant Human RELM-β, 500 μg £1,250.00
GFH160-1000 Recombinant Human RELM-β, 1 mg £1,950.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human RELM-β has a predicted Mw of 19.0 kDa (each monomer is 9.5 kDa).

Description

Resistin-like molecule-β (RELM-β) is a member of the RELM-family of secreted proteins containing conserved C-terminus cysteines. The RELM-family consists of resistin (FIZZ3), RELM-α (FIZZ1), RELM-β (FIZZ2), and RELM-γ (FIZZ4). Resistin and RELM-β are the only RELM-family members found in humans, whereas all four RELM-family members are present in rodents. RELM-β functions to increase fibroblast proliferation and differentiation, resulting in airway remodelling and increased inflammation.

Activity Assay

Activity to be determined.

AA Sequence

MQCSLDSVMD KKIKDVLNSL EYSPSPISKK LSCASVKSQG RPSSCPAGMA VTGCACGYGC GSWDVQLETT CHCQCSVVDW TTARCCHLT

Alternative Names

Resistin-like molecule-β, RELM β, FIZZ2
Product Details
Length 89 / 178 aa
Molecular Weight 9.5 / 19.0 kDa
Structure Dimer
Source E. coli
Accession Number Q2UXL7
Purity ≥90% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile 0.1% Trifluoroacetic Acid (TFA) at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.