Extracellular vesicles as a minimally invasive diagnostic source and active metabolic machines
Thursday, June 20th 2019 - 2:00 PM (BST), 3:00 PM (CEST)
*If you are unable to attend at this time, please register and a link will be sent to you with the recorded version.
Extracellular vesicles (EV) are secreted by all cells in the body in order to communicate with other nearby or distant cells, and to modify their environment contributing to tissue homeostasis. They carry a particular cargo that depends on the cellular status and cell type of origin, and include proteins, different biotypes of nucleic acids, lipids and metabolites. In this webinar, I will discuss how the EV cargo is used as a source to elucidate non-invasive biomarkers putting special emphasis in approaches that could accelerate the translation into the clinic. I will also highlight that EVs are not only carriers of molecules, they are also active nano-machines containing active enzymes that modify their environment and influencing different patho-physiological processes including endothelial function, cancer and metabolic disorders.
Prof Juan Manuel Falcon-Perez
IKERBASQUE Research Professor, Head of Exosomes Laboratory and Metabolomics Platform, CIC bioGUNE, CIBERehd, Spain