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Life Sciences Innovator 2023

Supporting your research

Life science researchers are working to address urgent global challenges. From rare diseases to pandemics, hunger and environmental destruction, your research is contributing to our shared future.

At Cell Guidance Systems, we are focussed on supporting your efforts. We provide a range of innovative products and services that make your research more effective by enhancing, simplifying and accelerating experimental workflow.

We provide our best to you. So you can give your best to the world. Together, we are making a difference.

Cell Guidance Systems Blog

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Life Sciences Innovator 2023

Life Sciences Innovator 2023

Cell Guidance Systems is pleased to announce that we have been selected as a UK Life Sciences Innovator 2023. The Life Sciences Innovator Showcase is a community of UK companies bringing innovative solutions as they ‘Go Global’ and connect with partners around the world.

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Exosome protein glycosylation patterns

Exosome protein glycosylation patterns

Glycosylation is the addition of glycan groups to proteins. This affects about 50% of proteins, including exosomal proteins, modulating their function. This impacts and reflects states of health and disease. As well as characterizing exosome glycosylation states for diagnostic purposes, glycosylation control strategies for therapeutic applications are in development.

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Targeting in-vivo protein delivery

Targeting in-vivo protein delivery

Recombinant proteins provide a powerful research tool and have also transformed the treatment of many diseases. From the smallest peptide to larger proteins, such as antibodies, how proteins are delivered and reach their target is critical to their function and just as important as their activity on the target.

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Jelly on a plate

Jelly on a plate

Major differences in cell behaviour develop when cells are cultured on petri dishes or hard material surfaces instead of their native biological environment. Biomaterials, particularly hydrogels, which can bridge this gap, are a key area of cell research.

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Membrane-less RNA compartments

Membrane-less RNA compartments

Preserving maternal RNA transmitted by an oocyte to its progeny is an essential aspect of oogenesis, yet not much is known about how this is achieved in mammalian species. In a recent issue of Science, researchers at the Max Planck Institute in Gottingen, Germany [Cheng et al. (2022)] uncovered the MARDO, a novel structure that may help answer this longstanding question.

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ELMs: Engineered living materials adapting to life

ELMs: Engineered living materials adapting to life

Living cellular structures that can respond to their environment are being developed. These structures seek to revolutionise the methods of traditional material technology and offer ways to address real-life challenges in medicine, biotechnology and sustainability.

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Extracellular vesicle corona

Extracellular vesicle corona

A major challenge of working with exosomes and other types of extracellular vesicles (EVs) is their characterization and agreeing parameters that define each group. Recently, this task has become even more challenging with a dawning realization that proteins (and nucleic acids) loosely associated with the surface of exosomes, once thought to be artefacts of purification, are functionally important.

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How can protein instability be fixed?

How can protein instability be fixed?

Purified recombinant proteins are used in products ranging from biological soap powders to cutting-edge medicines. The rate at which these proteins degrade is critical to their function. Technologies that address the rate of degradation and enable novel applications can transform the value of a protein

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