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Life Sciences Innovator 2023

Supporting your research

Life science researchers are working to address urgent global challenges. From rare diseases to pandemics, hunger and environmental destruction, your research is contributing to our shared future.

At Cell Guidance Systems, we are focussed on supporting your efforts. We provide a range of innovative products and services that make your research more effective by enhancing, simplifying and accelerating experimental workflow.

We provide our best to you. So you can give your best to the world. Together, we are making a difference.

Cell Guidance Systems Blog

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Do artificial sweeteners suppress the immune system?

Do artificial sweeteners suppress the immune system?

It is said that a drug without side effects is a drug without efficacy. Could the same be true of artificial sweeteners? Are we hoping too much that the sweetness we crave can be satisfied without the normal cost in calories, cavities and surges in blood sugar levels?

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Crystals in humans

Crystals in humans

Look hard enough and microscopic crystals are common in animals, including humans. Naturally occurring crystals in-vivo play important roles in health as well as disease. Recombinant protein crystals are also being used, or are in development, as drug delivery systems providing therapies to treat diseases including diabetes, cancer, osteoarthritis and macular degeneration.

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Controlled protein drug delivery

Controlled protein drug delivery

When proteins are used therapeutically, each protein and its target pair present unique challenges for delivery. Placing proteins in the right place (targeting) for a sufficient period (sustained delivery) to achieve efficacy requires solutions appropriate to each drug.

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Adapt and die: Does innate immunity target pathogen mutation?

Adapt and die: Does innate immunity target pathogen mutation?

Pattern recognition is one of the mechanisms by which the immune system discriminates pathogens from self. Immune cells are not simply identifying common pathogenic patterns, but instead, respond to fragments of pathogens released during unsuccessful pathogenic adaptation activities.

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Your liver disease and its cytokines

Your liver disease and its cytokines

If you are an adult, there is a high probability you already have liver disease. Even if you are of average weight and teetotal. Non-alcoholic fatty liver disease (NAFLD) now affects more than 30% of the world's population, a number that has risen rapidly over the last 20 years. Cytokines are key modulators of liver disease and understanding their role may be key to improved therapies.

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Cultured insect cells: making insects palatable

Cultured insect cells: making insects palatable

By 2050, the world population is expected to exceed nine billion, putting future global food security at risk. Animal-based food production contributes significantly to climate change. Although plant-based foods have a much lower environmental footprint than their counterparts, they do not satisfy everyone’s tastes or nutritional requirements. In this instance, switching towards an insect-based diet might just be the sustainable option we need to address food insecurities while also being greener on the planet.

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The enemy within: immune cell invading pathogens

The enemy within:  immune cell invading pathogens

As pathogens evolve, they develop ingenious survival strategies. Perhaps some of the most fascinating are the pathogens that have hit upon the strategy of taking up residence in the very cells tasked with their termination: phagocytic immune cells. This strategy also makes the task of clearing infections using drugs very challenging.

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