More EVs. Less effort. Lower cost.
The EVlution™ TFF System delivers high-yield, high-purity EV purification from up to 3 litres of starting material - in just 90 minutes. Unlike ultracentrifugation, EVlution™ is affordable, easy to use, and requires minimal hands-on time, freeing you to focus on what matters most: your research.
Its innovative Switch Flow™ technology reduces retentate volume to under 10 mL, maximising recovery while minimising loss. The compact, modular design supports 12 interchangeable polyethersulfone hollow fibre cartridge sizes, including the widely used 300 kDa and 500 kDa options optimised for EV concentration. Filters are reusable up to 20 times, keeping running costs low. EVlution™ pairs seamlessly with Exo-spin™ purification columns for a complete, end-to-end EV workflow.
Whether you're concentrating EVs, depleting FBS-associated particles, or performing buffer exchange, EVlution™ has you covered.
We compare the criteria that actually determine delivery outcomes: cargo loading, targeting, immune handling, manufacturability, analytical control and regulatory precedent.
Why is SEC becoming more popular, and when is ultracentrifugation still useful?
Why self-assembling peptide hydrogels flow under shear and re-heal after it: the mechanism, the rheology tests that matter, and rules for injection and printing.
This article sets out the four classes of composite, explains why charge compatibility decides whether a blend succeeds or precipitates, and gives a practical route to designing and characterising a composite based on PeptiGel.
A question that surfaces repeatedly in extracellular vesicle (EV) method development is whether two desirable properties can be held at the same time: a complete, unbiased EV population isolated without affinity capture, and a preparation that carries no risk of contaminating virus.
Diafiltration, the process of adding fresh buffer to a sample while simultaneously removing permeate, extends the tangential flow filtration technique into a far more powerful tool
All biomedical researchers want to see their work make a real-world impact. The odds are stacked against some fields
The combination of Tangential Flow Filtration (TFF) and size exclusion chromatography (SEC) is a widely used workflow for the isolation of virus-like proteins (VLPs).
