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Accelerate your research

We provide innovative products and services for life science research.

Our sustained-release PODS growth factors, conventional growth factors, and small molecules guide and support cells. Our wide range of surfaces and extracellular matrix products, including Softwell and the versatile PeptiGel self-assembling hydrogels enable more challenging cell culture. Our highly cited karyotyping service keeps track of cell stability.

For extracellular vesicle research, Cell Guidance Systems products and services enable the purification and subsequent analysis of exosomes and other EVs. We're here to support you in your research.

Cell Guidance Systems Blog

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Scaffold stiffness importance for 3D cell culture

Scaffold stiffness importance for 3D cell culture

Scaffolds have an important role to play in tissue engineering, as they are a substrate that can be used to mimic the native extracellular matrix (ECM). The properties of scaffolds have also been shown to affect cell behaviour such as cell attachment, differentiation and proliferation.

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Using PeptiInk® Alpha-1™ for bioprinting chondrocytes

Using PeptiInk® Alpha-1™ for bioprinting chondrocytes

The complex structure of articular cartilage and its lack of vasculature present particular challenges for regenerative medicine. A recent study led by researchers at University College London explored the utility of PeptiInk Alpha 1 for printing 3D chondrocyte structures.

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PeptiGel® Alpha 2 in a model of intracerebral haemorrhage

PeptiGel® Alpha 2 in a model of intracerebral haemorrhage

Hydrogel matrices, either on their own or combination with implanted cells, are capable of supporting the repair of tissue injuries. A new study from researchers at Manchester University, available as a pre-print, demonstrates the safety and cell-proliferative action of PeptiGel Alpha 2 injected intracerebrally in a rat model of haemorrhagic stroke.

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Comparing BME vs PeptiGel hydrogels

Comparing BME vs PeptiGel hydrogels

When you think about 3D cell culture, you probably think about Matrigel, after all, it is the current market leader in 3D cell culture. Matrigel does have limitations, however, which is something that Cell Guidance Systems are tackling with a fully synthetic alternative. This blog article will discuss the differences between Matrigel and PeptiGels, fully synthetic (and 100% animal-free) and the benefits you can expect from each.

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Hydrogels and tunability

Hydrogels and tunability

Hydrogels are being increasingly for a wide range of biomedical applications including cell culture, drug delivery, tissue engineering and wound healing. This research has opened up new opportunities to provide materials that are triggerable and tuneable.

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What is scaffold-based 3D culture?

What is scaffold-based 3D culture?

Before a drug is deemed suitable for patients, it must undergo a rigorous testing process and cost-effectiveness analyses. The testing begins in a lab where researchers investigate the process behind a disease at either cellular or molecular level. In the past, this has been completed using 2D cell culture, which is convenient and accessible, but more often, cells are grown in a complex 3D environment.

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