Human Liver Microsomes, 50-donor Pooled

Product Description

Human liver microsomes pooled from 50 gender-balanced individuals. 

Note: Samples are available for evaluation with the first order. The minimum order for this product is 10 vials. Please ask for a quote for >100 vials.

The cytochrome P450 enzyme (CYP) family play a key role in hepatic elimination that occurs in the endoplasmic reticulum. Liver microsomes are the most convenient way to investigate CYP-mediated metabolism. Microsomes are a useful in vitro testing system as they contain all CYP enzymes and ensure the CYP kinetic measurements are not confused with other metabolic processes or cellular uptake.  

Microsomes are available from a range of species and suitable for a variety of experiments:

• Metabolite characterization
• Cytochrome P450 inhibition studies
• Metabolic stability