PeptiGel® Alpha 2™
Synthetic Self-Assembling Peptide Hydrogels
PeptiGels® are ready-to-use fully synthetic peptide hydrogels that are biologically relevant and formulated to meet your cells’ needs. PeptiGels® are used for 2D and 3D cell culture and are specifically designed with a range of mechanical properties and chemical functionalities to mimic the native cellular micro-environment to allow the growth of any cell type.
Product Description
PeptiGel® Alpha 2™ is a ready-to-use fully synthetic positively charged peptide hydrogel. PeptiGel® Alpha 2™ is biologically relevant, mimics the extracellular matrix and is suitable for the culture of a variety of cells, including neuronal cells.
PeptiGel® Alpha 2™ is a stiffer hydrogel when compared to Alpha 4 but has consistent mechanical stiffness (G’) and pore size, resulting in excellent reproducible results. PeptiGel® Alpha 2™ can be used for both in-vitro and in-vivo applications with physiologically and clinically relevant results.
Case Studies
PeptiGel® outperforms Matrigel™
PeptiGel® Alpha 2™ supports quicker growth of fully formed gastro-intestinal organoids than Matrigel™.
Tailored PeptiGel® properties mimic the mechanical and chemical environment of healthy and cancer tissue
Tumour mimicking (stiff and acidic) PeptiGel® Alpha 2™ results in increased proliferation of Pancreatic Ductal Adenocarcinoma suit-2 cells.
References
- Clough HC, O'Brien M, Zhu X, Miller AF, Saiani A, Tsigkou O. (2021) Neutrally charged self-assembling peptide hydrogel recapitulates in vitro mechanisms of breast cancer progression. Materials Science and Engineering 127: 112200
| Product Details | |
|---|---|
| Charge |
Positive (+1) |
| Mechanical Properties (kPa) |
6.0 - 8.0 |
| Functional motif: GFOGER (Collagen) |
No |
| Functional motif: RGD (Fibronectin) |
No |
| Stability and Storage |
At least 6 months when stored at 4°C as supplied. |
