PeptiGel® Gamma 2™
Demonstrated Compatible Cells
Dorsal Root Ganglion Neurons | Pancreas Suit-2
Synthetic Self-Assembling Peptide Hydrogels
PeptiGels® are ready-to-use fully synthetic self-assembling peptide hydrogels that are biologically relevant and formulated to meet your cells’ needs. PeptiGels® are used for 2D and 3D cell culture and are specifically designed with a range of mechanical properties and chemical functionalities to mimic the native cellular micro-environment to allow the growth of any cell type.
Product Description
PeptiGel® Gamma 2™ is a ready-to-use fully synthetic positively charged peptide hydrogel. PeptiGel® Gamma 2™ is biologically relevant, mimics the extracellular matrix and is suitable for the culture of a variety of cells, including neuronal cells.
PeptiGel® Gamma 2™ is a softer hydrogel when compared to Alpha 2 but has consistent mechanical stiffness (G’) and pore size, resulting in excellent reproducible results. PeptiGel® Gamma 2™ can be used for both in-vitro and in-vivo applications with physiologically and clinically relevant results.
Trial Size and Value Starter Pack
When beginning to work with PeptiGels®, we recommend purchasing our 1 ml trial pack sizes for new users. This allows you to evaluate the benefits of PeptiGel and PeptiInk hydrogels in your culture system at a very low cost. New users can purchase up to five 1 ml pack sizes.
We also offer a Value Starter Pack. This includes five versions of PeptiGel® of your choice (1 ml each) to test with your cells to enable you to identify the most suitable matrix environment. The Pack also includes a Gilson positive displacement pipette (various sizes are available), a box of sterile tips and a pack of Greiner Thincerts. Contact us for additional information.
Case Studies
Tailored PeptiGel® properties mimic the mechanical and chemical environment of healthy and cancer tissue
Healthy tissue mimicking PeptiGel® Gamma 2 supports the growth of Pancreatic Ductal Adenocarcinoma suit-2 cells.
References
- Norton B, Quirk A and Matsuoka AJ. (2023) Unraveling the Mechanisms of Vestibular Neuron Formation from Human Induced Pluripotent Stem Cells. Tissue Engineering
- Lachowski D, Matellan C, Cortes E, Saiani A, Miller AF and del Río Hernández AE. (2021) Self-assembling polypeptide hydrogels as a platform to recapitulate the tumor microenvironment. Cancers 13(13): 3286.
- Wei W, Cardes F, Hierlemann A and Modena MM. (2023) 3D In Vitro Bloodâ€Brainâ€Barrier Model for Investigating Barrier Insults. Advanced Science 10(11): 2205752.
- Clough HC, O'Brien M, Zhu X, Miller AF, Saiani A and Tsigkou O. (2021) Neutrally charged self-assembling peptide hydrogel recapitulates in vitro mechanisms of breast cancer progression. Materials Science and Engineering 127: 112200
| Product Details | |
|---|---|
| Formulation |
Synthetic, self-assembling peptide hydrogel |
| Charge |
Positive (+1) |
| pH |
3.5 - 4.2 |
| Mechanical Properties (kPa) |
0.5 - 1.5 |
| Biocompatibility |
Non-toxic, safe for animal studies |
| Biodegradability |
Biodegradable, supports cell activities |
| Functional motif: GFOGER (Collagen) |
No |
| Functional motif: RGD (Fibronectin) |
No |
| Stability and Storage |
At least 6 months from receipt when stored at 4°C as supplied. |
| Shipping Temperature |
Ambient |
