EV and Exosome Services
Cell Guidance Systems provides a comprehensive outsourced extracellular vesicle isolation service and exosome characterisation service for research laboratories at every stage of their EV journey. Whether you need a fast first-pass EV analysis service or a fully MISEV-compliant workflow complete with nanoparticle tracking analysis, western blot and ExoLISA exosome biomarker detection, our experienced Cambridge team can support you. All isolations use our own widely-cited Exo-spin SEC exosome isolation kits; NTA measurements are performed on the ZetaView instrument. We accept exosome isolation from cell culture media (10 ml–1000 ml) and exosome isolation from plasma or sera (0.1 ml–5 ml). Optional exosome freeze drying is available for samples requiring long-term stability.
EV & Exosome Service Components |
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Services Offered |
Sample Types & Turnaround |
Get Started |
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Cell culture media Plasma / sera Pre-purified EVs Turnaround time |
Not sure which package suits your project? Our team will advise at no obligation. |
We support labs with their extracellular vesicle (EV) and exosome research efforts. From labs new to the field, to expert labs just requiring additional support, we offer flexible in-house services designed to accelerate your EV research journey.
EV Service Options
Service packages are available for popular service combinations.
EV Isolation & Analysis Service Package Offerings |
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Service |
Service Description |
Basic package |
MISEV* Analysis Package |
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Isolation |
Exosomes are isolated from your sample using our own widely cited Exo-spin EV isolation kits |
Included |
Included |
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Protein Quantification |
The total concentration of protein present in the isolated exosomes is quantified via an industry-standard BCA assay |
Included |
Included |
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Nanoparticle Tracking Analysis (NTA) |
The total size and particle concentration of your exosomes is analysed via a Particle Metrix Zetaview® instrument |
Included | Included |
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Lipid Quantification |
The total concentration of fatty acids within your isolated exosomes is measured using a colourimetric assay |
Included | |
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Western Blot |
We use state-of-the-art digital equipment to detect the presence of the most common exosome tetraspanin biomarkers (CD9, CD81 & CD63) |
Included | |
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Exosome Biomarker Detection Assay (ExoLISA™) |
ExoLISA™ time-resolved fluorescence (TRF) assays, developed to measure the abundance of CD9, CD63, or CD81 protein specifically associated with exosomes, are used |
Included | |
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Transmission electron microscopy |
Expert microscopy of extracellular vesicles using a Zeiss CrossBeam 550 electron microscope |
Optional |
Optional |
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Freeze-drying |
Your isolated exosomes are freeze-dried by our experienced technicians, enabling longer storage and retained bioactivity |
Optional | Optional |
You may select the Basic or MISEV package or request a quote for any individual assay.
*MISEV - Minimal information for studies of extracellular vesicles