Purified Exosomes

Characterised, freeze-dried EVs from a variety of sources

Instant Exosomes™ are a range of well-characterised, freeze-dried extracellular vesicles (EVs) and exosomes, prepared from human cancer cell lines, mesenchymal stem cells (MSCs) and mouse serum. Each lot is produced using a validated isolation workflow combining differential precipitation and size exclusion chromatography (SEC), providing consistent, publication-quality material without the need for in-house isolation.

Freeze-drying enables long-term stability and straightforward reconstitution, making Instant Exosomes™ ideal for laboratories that require reliable exosome reference material on demand.

Every batch of Instant Exosomes™ undergoes rigorous characterisation before release:

• Particle concentration and size distribution by nanoparticle tracking analysis (NTA) using a ZetaView® instrument (Particle Metrix GmbH)
• Total protein content quantified by BCA assay
• Exosomal marker expression (CD9, CD63 and CD81) confirmed using the ExoLISA™ exosome detection assay

Full characterisation data is provided with each product, supporting downstream data interpretation and experimental reproducibility.

Instant Exosomes™ are ready-to-use upon reconstitution and are suitable for a broad range of research applications:

• Protein biomarker discovery and analysis
• Functional cell-based assays
• Exosomal nucleic acid profiling (RNA and miRNA)
• Electron microscopy and nanoparticle imaging
• Assay development and positive controls
• Liquid biopsy research and cancer biomarker studies

EVs are available from cell lines and serum including:

• Mouse serum
• Colon cancer (COLO205, HCT116)
• Hepatocellular cancer (Huh7, HepG2)
• Kidney (HEK293)
• Melanoma (A375)
• Mesenchymal stem cells (MSCs)
• Neuroblastoma (SH-SY5Y)
• Prostate cancer (LnCAP)