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Non-Parenchymal Cells

Hepatocytes alone are not able to fully represent in vivo functionality during toxicology evaluations. Co-cultures are a liver-derived in vitro model system that aims to preserve liver-specific morphology and functionality beyond what is provided by pure parenchymal cell cultures. 

Co-cultures can be prepared using hepatocytes and non-parenchymal cell (NPC) cultures which, has been evidenced to be one of the most successful models for maintaining functionality in vitro when examining drug-related hepatotoxicity. NPCs characterized for the co-culture with hepatocytes in basement membrane overlay.


Non-parenchymal Cells, Human-derived $500.00