Recombinant Human β-defensin 3

Code Description Price Qty
GFH192-5 Recombinant Human β-Defensin 3, 5 μg £50.00
GFH192-20 Recombinant Human β-Defensin 3, 20 μg £120.00
GFH192-100 Recombinant Human β-Defensin 3, 100 μg £325.00
GFH192-100x10 Recombinant Human β-Defensin 3, 100 μg x 1 £1,375.00
GFH192-1000 Recombinant Human β-Defensin 3, 1 mg £1,375.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human β-defensin 3 has a predicted Mw of 5.2 kDa.

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PODS Growth Factors

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Description

β-defensin 3 is a member of the defensin class of antimicrobial peptides. β-defensins exert host defense responses against viruses, bacteria, and fungi through the binding and permeabilizing of microbial membranes. β-defensin 3 expression is stimulated by IFN-γ and is an important molecule during adaptive immunity. β-defensin 3 functions to activate monocytes and mast cells, and has antibacterial functions towards Gram-negative and Gram-positive bacteria.

Activity Assay

Activity to be determined.

AA Sequence

GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK

Alternative Names

BDF-3, BD-3
Product Details
Length 45 aa
Molecular Weight 5.2 kDa
Structure Monomer
Source E. coli
Accession Number P81534
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile 10 mM acetic acid at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.