Exact Amount™The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.
CHIR99021 is an aminopyrimidine derivative. CHIR99021 inhibits GSK3 beta (IC50 = 6.7 nM) and GSK3 alpha (IC50 = 10 nM) and functions as a WNT pathway activator.
CHIR99021 is widely used in definitive endoderm differentiation protocols.
CHIR-99021, CHIR 99021, CT 99021, CHIR 911, GSK-3 Inhibitor XVI
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2. Tsukiyama, T. and Ohinata, Y. 2014. PLoS One. 9(4): e95329. PMID: 24736627