PD0325901
PD0325901
Exact Amount™
The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.Activity
PD0325901, a MEK inhibitor, is a synthetic organic molecule targeting mitogen-activated protein kinase (MAPK/ERK kinase or MEK).
Effect
PD0325901 has potential antineoplastic activity. This molecule inhibits the growth of melanoma cell lines in-vitro and in-vivo.
Alternative Names
PD 0325901, PD325901, PD-0325901
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
References
1. Henderson, YC., et al. 2010. Mol Cancer Ther. 9(7): 1968-1976. PMID: 20587665
2. Ying, QL., et al. 2008. Nature. 453(7194): 519-523. PMID: 18497825
| Product Details | |
|---|---|
| Formula | C16H14F3IN2O4 |
| Molecular Weight | 482.19 |
| CAS Number | 391210-10-9 |
| Purity | >99% |
| Solubility | DMSO, ethanol |
| Stability and Storage | Stable at -20°C. Keep away from direct sunlight. |
