Recombinant Mouse Exodus-2 / CCL21

Code Description Price Qty
GFM35-5 Recombinant Mouse Exodus-2 / CCL21, 5 μg £50.00
GFM35-20 Recombinant Mouse Exodus-2 / CCL21, 20 μg £120.00
GFM35-100 Recombinant Mouse Exodus-2 / CCL21, 100 μg £310.00
GFM35-100x10 Recombinant Mouse Exodus-2 / CCL21, 100 μg x 10 £1,375.00
GFM35-1000 Recombinant Mouse Exodus-2 / CCL21, 1 mg £1,375.00

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PODS Growth Factors

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Description

Exodus-2, also known as CCL21, is a chemokine that is strongly produced in the human lymph nodes and spleen. Exodus-2 signals through the chemokine receptor CCR7 to regulate thymocyte and activated T cell migration. Exodus-2 also mediates the homing of lymphocytes to the lymphatic system. Human and mouse Exodus-2 proteins share greater than 85% amino acid sequence identity.

Activity Assay

Mouse Exodus-2 is fully biologically active when compared to standard. The activity is determined by the ability to chemoattract 5 - 10 day old cultures of human peripheral blood lymphocytes at a concentration between 200 - 600 ng/ml. There is no data currently available.

AA Sequence

SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG

Alternative Names

CCL21, 6Ckine, exodus 2, exodus2
Product Details
Length 110 aa
Molecular Weight 12 kDa
Structure Monomer
Source E. coli
Accession Number P84444
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.