Recombinant Mouse IL-27 / EBI-3
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PODS® Growth Factors
The product is currently not available as PODS®, please check back in the future.Description
Epstein-Barr virus induced gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin-12 (IL-12). EBI-3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form interleukin-27 (IL-27), and with p35 to form interleukin-35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.Activity Assay
Activity to be determined.AA Sequence
MALVALSQPR VQCHASRYPV AVDCSWTPLQ APNSTRSTSF IATYRLGVAT QQQSQPCLQR SPQASRCTIP DVHLFSTVPY MLNVTAVHPG GASSSLLAFV AERIIKPDPP EGVRLRTAGQ RLQVLWHPPA SWPFPDIFSL KYRLRYRRRG ASHFRQVGPI EATTFTLRNS KPHAKYCIQV SAQDLTDYGK PSDWSLPGQV ESAPHKPAlternative Names
IL-35/EBI-3, IL-27/EBI-3, interleukin-27, interleukin 27, IL27, IL 27, EBI-3 subunit, epstein-barr virus induced gene-3| Product Details | |
|---|---|
| Length | 207 aa |
| Molecular Weight | 23 kDa |
| Structure | Monomer |
| Source | E. coli |
| Accession Number | O35228 |
| Purity | ≥90% determined by reducing and non-reducing SDS-PAGE |
| Endotoxin Level | ≤1.00 EU/μg as measured by kinetic LAL |
| Formulation | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) |
| Reconstitution | Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions. |
| Stability and Storage |
12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed. |
