Recombinant Mouse IL-27 / EBI-3

Code Description Price Qty
GFM57-2 Mouse IL-27 / EBI-3, 2 μg $65.00
GFM57-10 Mouse IL-27 / EBI-3, 10 μg $165.00
GFM57-100 Mouse IL-27 / EBI-3, 100 μg $635.00
GFM57-1000 Mouse IL-27 / EBI-3, 1 mg $5,240.00

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Description

Epstein-Barr virus induced gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin-12 (IL-12). EBI-3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form interleukin-27 (IL-27), and with p35 to form interleukin-35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.

Activity Assay

Activity to be determined.

AA Sequence

MALVALSQPR VQCHASRYPV AVDCSWTPLQ APNSTRSTSF IATYRLGVAT QQQSQPCLQR SPQASRCTIP DVHLFSTVPY MLNVTAVHPG GASSSLLAFV AERIIKPDPP EGVRLRTAGQ RLQVLWHPPA SWPFPDIFSL KYRLRYRRRG ASHFRQVGPI EATTFTLRNS KPHAKYCIQV SAQDLTDYGK PSDWSLPGQV ESAPHKP

Alternative Names

IL-35/EBI-3, IL-27/EBI-3, interleukin-27, interleukin 27, IL27, IL 27, EBI-3 subunit, epstein-barr virus induced gene-3
Product Details
Length 207 aa
Molecular Weight 23 kDa
Structure Monomer
Source E. coli
Accession Number O35228
Purity ≥90% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.