Recombinant Mouse RELM-γ

Code Description Price Qty
GFM89-5 Mouse RELM-γ, 5 μg $65.00
GFM89-25 Mouse RELM-γ, 25 μg $165.00
GFM89-100 Mouse RELM-γ, 100 μg $435.00
GFM89-1000 Mouse RELM-γ, 1 mg $2,950.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Mouse RELM-γ has a predicted Mw of 18.9 kDa (each monomer is 9.4 kDa). The dimer runs higher in the gel.

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Description

Resistin-like molecule-γ (RELM-γ) is a member of the RELM-family of secreted proteins containing C-terminal cysteines. The RELM-family consists of resistin (FIZZ3), RELM-α (FIZZ1), RELM-β (FIZZ2), and RELM-γ (FIZZ4). RELM-γ is secreted by peripheral blood granulocytes, bone marrow, spleen, intestine, and lung. RELM-γ functions to promote and regulate promyelocytic differentiation, in addition to regulating nutrient-associated insulin sensitivity in the intestinal tract. Rodents secrete all four RELM-family members, whereas resistin and RELM-β are the only RELM-family members found in humans.

Activity Assay

There is no biological assay data available but protein content is validated by western blot.

AA Sequence

MEGTLESIVE KKVKELLANR DDCPSTVTKT FSCTSITASG RLASCPSGMT VTGCACGYGC GSWDIRDGNT CHCQCSTMDW ATARCCQLA

Alternative Names

Resistin-like molecule-γ, RELM γ, FIZZ4
Product Details
Length 89 / 178 aa
Molecular Weight 9.4 / 18.9 kDa
Structure Dimer
Source E. coli
Accession Number Q7TM98
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.