Recombinant Human Chemerin

Code Description Price Qty
GFH36-5 Human Chemerin, 5 μg $75.00
GFH36-25 Human Chemerin, 25 μg $189.00
GFH36-100 Human Chemerin, 100 μg $469.00
GFH36-1000 Human Chemerin, 1 mg $3,382.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human Chemerin has a predicted Mw of 16 kDa.

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PODS® Growth Factors

This growth factor is also available as PODS® for sustained release, see here.

Description

Chemerin is a chemoattractant adipokine that is expressed in white adipose, liver, skin, and lung tissues. Chemerin is a ligand for the G protein-coupled receptor chemokine-like receptor 1 (ChemR23), which is expressed on dendritic cells, macrophages, and adipocytes. Chemerin functions to recruit macrophages to sites of tissue damage and inflammation. Chemerin is also a regulator of glucose metabolism in the liver.

Activity Assay

Human Chemerin is fully biologically active when compared to standard. The activity can be determined by its ability to chemoattract human Chem23R transfected BaF3 mouse pro-B cells and it is typically 4 - 20 ng/ml.

AA Sequence

MELTEAQRRG LQVALEEFHK HPPVQWAFQE TSVESAVDTP FPAGIFVRLE FKLQQTSCRK RDWKKPECKV RPNGRKRKCL ACIKLGSEDK VLGRLVHCPI ETQVLREAEE HQETQCLRVQ RAGEDPHSFY FPGQFAFS

Alternative Names

Tazarotene-induced gene 2, TIG2, RARRES2
Product Details
Length 138 aa
Molecular Weight 16 kDa
Structure Monomer
Source E. coli
Accession Number Q99969
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.