Recombinant Human CTGF

Code Description Price Qty
GFH60-5 Recombinant Human CTGF, 5 μg £50.00
GFH60-20 Recombinant Human CTGF, 20 μg £120.00
GFH60-100 Recombinant Human CTGF, 100 μg £310.00
GFH60-100x10 Recombinant Human CTGF, 100 μg x 10 £1,650.00
GFH60-1000 Recombinant Human CTGF, 1 mg £1,650.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human CTGF has a predicted Mw of 11.2 kDa.

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PODS Growth Factors

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Description

Connective Tissue Growth Factor (CTGF) is a mitogen that is secreted by vascular endothelial cells in response to basic fibroblast growth factor (FGF-2) or vascular endothelial growth factor (VEGF). CTGF promotes cell growth, migration, adhesion, and survival of endothelial cells. CTGF is also important during osteogenesis, chondrogenesis, and skeletogenesis. CTGF has an insulin-like growth factor binding protein (IGFBP) domain, a thrombospondin type 1 repeat (TSR) domain, and a C-terminal cysteine knot motif.

Activity Assay

Human CTGF is fully biologically active when compared to standard. The activity is determined by the dose-dependent induction of HUVEC cells proliferation.

AA Sequence

MGKKCIRTPK ISKPIKFELS GCTSMKTYRA KFCGVCTDGR CCTPHRTTTL PVEFKCPDGE VMKKNMMFIK TCACHYNCPG DNDIFESLYY RKMYGDMA

Alternative Names

Connective Tissue Growth Factor, IGF-binding protein 8, IGFBP8, IGFBP-8, IBP-8, CCN2, HCS24,insulin-like growth factor-binding protein HCS24, hypertrophic chondrocyte-specific protein 24, NOV2, CCN family member, 2MGC102839
Product Details
Length 98 aa
Molecular Weight 11.2 kDa
Structure Monomer
Source E. coli
Accession Number P29279
Purity ≥90% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.