Recombinant Human Exodus-2 / CCL21

Code Description Price Qty
GFH06-5 Recombinant Human Exodus-2 / CCL21, 5 μg £50.00
GFH06-20 Recombinant Human Exodus-2 / CCL21, 20 μg £120.00
GFH06-100 Recombinant Human Exodus-2 / CCL21, 100 μg £310.00
GFH06-100x10 Recombinant Human Exodus-2 / CCL21, 100 μg x 10 £1,375.00
GFH06-1000 Recombinant Human Exodus-2 / CCL21, 1 mg £1,375.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human Exodus-2 has a predicted Mw of 12.3 kDa, but runs approximately 16 kDa on SDS-PAGE.

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PODS Growth Factors

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Description

Exodus-2, also known as CCL21, is a chemokine that is strongly produced in the human lymph nodes and spleen. Exodus-2 signals through the chemokine receptor CCR7 to regulate thymocyte and activated T cell migration, but is not chemotactic for monocytes. Exodus-2 also mediates the homing of lymphocytes to the lymphatic system. Human and mouse Exodus-2 share > 85% amino acid identity.

Activity Assay

Activity to be determined.

AA Sequence

SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P

Alternative Names

CCL21, 6Ckine, secondary lymphoid tissue chemokine, SLC
Product Details
Length 111 aa
Molecular Weight 12.3 kDa
Structure Monomer
Source E. coli
Accession Number O00585
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.