Recombinant Human GRO-α / CXCL1

Code Description Price Qty
GFH32-5 Human GRO-α, 5 μg $65.00
GFH32-25 Human GRO-α, 25 μg $165.00
GFH32-100 Human GRO-α, 100 μg $410.00
GFH32-1000 Human GRO-α, 1 mg $2,950.00
Induced chemotaxis of human neutrophils assay for Human GRO-α.
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human GRO-α has a predicted Mw of 7.9 kDa.

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Description

Growth regulated protein α (GRO-α), also known as CXCL1, is a chemokine that has mitogenic properties and is a neutrophil chemoattractant. GRO-α is secreted by macrophages, epithelial cells, neutrophils, and melanomas. GRO-α signals through the CXCR2 chemokine receptor and is important during spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing.

Activity Assay

Human GRO-α is fully biologically active when compared to standard. The activity is determined by the induced chemotaxis of human neutrophils.

AA Sequence

ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

Alternative Names

Growth regulated protein α, GROa, GROα
Product Details
Length 73 aa
Molecular Weight 7.9 kDa
Structure Monomer
Source E. coli
Accession Number P09341
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.