Recombinant Human IL-16

Code Description Price Qty
GFH144-10 Human IL-16, 10 μg $189.00
GFH144-100 Human IL-16, 100 μg $728.00
GFH144-500 Human IL-16, 500 μg $3,536.00
GFH144-1000 Human IL-16, 1 mg $6,007.00
Induced chemotaxis of primary human T cells. A significant increase in migration over basal levels was reported in response to Human IL-16 starting at 5 ng/ml.
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human IL-16 has a predicted Mw of 13.4 kDa.

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Description

Interleukin-16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin-2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).

Activity Assay

Human IL-16 is fully biologically active when compared to standard. The activity is determined by the ability to induce chemotaxis of primary human T cells by Human IL-16.

AA Sequence

MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS

Alternative Names

Interleukin-16, interleukin 16, IL16, IL 16, lymphocyte chemoattractant factor, LCF, NIL16
Product Details
Length 130 aa
Molecular Weight 13.4 kDa
Structure Monomer
Source E. coli
Accession Number Q14005
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.