Recombinant Human IL-17E / IL-25

Code Description Price Qty
GFH149-5 Human IL-17E / IL-25, 5 μg $65.00
GFH149-25 Human IL-17E / IL-25, 25 μg $165.00
GFH149-100 Human IL-17E / IL-25, 100 μg $410.00
GFH149-1000 Human IL-17E / IL-25, 1 mg $2,950.00
Induced IL-8 production by human PBMC cells when cultured with Human IL-17E.

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Description

Interleukin-17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17BR receptor to stimulate the secretion of the proinflammatory Interleukin-8 (IL-8) chemokine and to induce the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB).

Activity Assay

Human IL-17E is fully biologically active when compared to standard. The activity is determined by the ability to produce IL-8 by human PBMC cells.

AA Sequence

MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT

Alternative Names

Insulin-like Growth Factor 1, somatamedin C, mechano growth factor, IGF-IA, IGF-IB, IGF-I, IGFI, insulin-like growth factor I, IGF1A1, insulin-like growth factor IA, insulin-like growth factor IB, MGF2, IBP1
Product Details
Length 146 / 292 aa
Molecular Weight 16.9 / 33.7 kDa
Structure Dimer
Source E. coli
Accession Number Q9H293
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.