Recombinant Human IL-7 (Animal-Free)

Code Description Price Qty
GFH11AF-2 Human IL-7 (Animal-Free), 2 μg $70.00
GFH11AF-10 Human IL-7 (Animal-Free), 10 μg $180.00
GFH11AF-100 Human IL-7 (Animal-Free), 100 μg $695.00
GFH11AF-1000 Human IL-7 (Animal-Free), 1 mg $5,765.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human IL-7 has a predicted Mw of 17.5 kDa.

Achieve Purchasing Synergy

Request a quote at quotes@cellgs.com for 2 or more vials of any Growth Factor to receive a discount. Discounts range from 5 to 20% according to the size of your order.

PODS® Growth Factors

The product is currently not available as PODS®, please check back in the future.

Animal-Free

This product is produced with no animal derived raw products. All processing and handling employs animal free equipment and animal free protocols.

Description

Interleukin-7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin-7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and Natural Killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity.

Activity Assay

Human IL-7 (Animal-Free) is fully biologically active when compared to standard. The activity is determined by the ability to induce mouse 2E8 cells proliferation and it is typically less than 1 ng/ml. This corresponds to an expected specific activity of 1 x 106 units/mg.

AA Sequence

MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH

Alternative Names

Interleukin-7, interleukin 7, IL7, IL 7, lymphopoietin 1, LP-1, pre-B cell factor
Product Details
Length 153 aa
Molecular Weight 17.5 kDa
Structure Monomer
Source E. coli
Accession Number P13232
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM acetic acid
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.