Recombinant Human NRG1-β

Code Description Price Qty
GFH46-10 Human NRG1-β, 10 μg $65.00
GFH46-50 Human NRG1-β, 50 μg $165.00
GFH46-100 Human NRG1-β, 100 μg $295.00
GFH46-1000 Human NRG1-β, 1 mg $1,310.00
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human NRG1-β has a predicted Mw of 7.6 kDa.

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Description

Neuregulin 1-β (NRG1-β) is one of many alternatively-spliced isoforms of the NRG1 gene and contains a soluble EGF-like domain. The EGF-like domain of NRG1-β signals through the ErbB2, ErbB3, and ErbB4 receptor tyrosine kinases. NRG1-β is an important growth factor involved in neuroinflammation, nerve regeneration, and cardiovascular processes.

Activity Assay

Activity to be determined.

AA Sequence

MSHLVKCAEK EKTFCVNGGE CFMVKDLSNP SRYLCKCPNE FTGDRCQNYV MASFYKHLGI EFMEAE

Alternative Names

Neuregulin 1 β, NGR β 1, heregulin, HRG1 β, neuregulin 1, Heregulinβ-1, heregulin beta 1
Product Details
Length 66 aa
Molecular Weight 7.6 kDa
Structure Monomer
Source E. coli
Accession Number Q02297-6
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.