Recombinant Human RANTES / CCL5

Code Description Price Qty
GFH138-5 Human RANTES, 5 μg $65.00
GFH138-20 Human RANTES, 20 μg $165.00
GFH138-100 Human RANTES, 100 μg $410.00
GFH138-1000 Human RANTES, 1 mg $2,950.00
Induced chemotaxis of human neutrophils assay for Human RANTES. Cells that migrated were counted using a luminescent substrate. Migration over basal levels was reported in response to Human RANTES starting at 1000 ng/ml.
Non-reducing (-) and reducing (+) conditions in a 4 - 20% Tris-Glycine gel stained with Coomassie Blue. 1 μg of protein was loaded in each lane. Human RANTES has a predicted Mw of 7.9 kDa.

Achieve Purchasing Synergy

Request a quote at quotes@cellgs.com for 2 or more vials of any Growth Factor to receive a discount. Discounts range from 5 to 20% according to the size of your order.

PODS® Growth Factors

The product is currently not available as PODS®, please check back in the future.

Description

Regulated upon activation, normal T cell expressed and secreted (RANTES), also known as CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28. RANTES functions to recruit immune cells to inflammatory sites.

Activity Assay

Human RANTES is fully biologically active when compared to standard. The activity is determined by the ability to induce chemotaxis of human neutrophils.

AA Sequence

SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS

Alternative Names

CCL5, TCP228, SIS-delta, SCYA5
Product Details
Length 68 aa
Molecular Weight 7.9 kDa
Structure Monomer
Source E. coli
Accession Number P13501
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.