Recombinant Mouse GDNF

Code Description Price Qty
GFM37-2 Recombinant Mouse GDNF, 2 μg £50.00
GFM37-10 Recombinant Mouse GDNF, 10 μg £120.00
GFM37-100 Recombinant Mouse GDNF, 100 μg £445.00
GFM37-100x10 Recombinant Mouse GDNF, 100 μg x 10 £2,495.00
GFM37-1000 Recombinant Mouse GDNF, 1 mg £2,495.00
Induced proliferation of C6 cells assay for Mouse GDNF. Cell proliferation was measured to calculate the ED50.

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PODS Growth Factors

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Description

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

Activity Assay

Mouse GDNF is fully biologically active when compared to standard. The activity is determined by a proliferation assay using C6 cells.

AA Sequence

MSPDKQAAL PRRENRNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCESAETMY DKILKNLSRS RRLTSDKVGQ ACCRPVAFDD DLSFLDDNLV YHILRKHSAK RCGCI

Alternative Names

ATF, HFB1-GDNF, ATF1, ATF-1, astrocyte-derived trophic factor 2, glial cell line derived neurotrophic factor
Product Details
Length 135 / 270 aa
Molecular Weight 15.1 / 30.2 kDa
Structure Dimer
Source E. coli
Accession Number P48540
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.