Recombinant Mouse IL-19

Code Description Price Qty
GFM75-2 Mouse IL-19, 2 μg $65.00
GFM75-10 Mouse IL-19, 10 μg $165.00
GFM75-100 Mouse IL-19, 100 μg $635.00
GFM75-1000 Mouse IL-19, 1 mg $5,240.00

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Description

Interleukin-19 (IL-19) is a member of the interleukin-10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin-20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin-6 (IL-6) and Tumor Necrosis Factor α (TNF-α) expression in monocytes, and promotes T helper 2 (Th2) cell-mediated immune responses. IL-19 production is up-regulated in resting monocytes following Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.

Activity Assay

Activity to be determined.

AA Sequence

MLRRCLISVD MRLIEKSFHE IKRAMQTKDT FKNVTILSLE NLRSIKPGDV CCMTNNLLTF YRDRVFQDHQ ERSLEVLRRI SSIANSFLCV QKSLERCQVH RQCNCSQEAT NATRIIHDNY NQLEVSSAAL KSLGELNILL AWIDRNHLET PAA

Alternative Names

Interleukin-19, interleukin 19, IL19, IL 19, melanoma differentiation associated-like protein
Product Details
Length 153 aa
Molecular Weight 17.7 kDa
Structure Monomer
Source E. coli
Accession Number Q8CJ70
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.