Recombinant Mouse IL-27 / p28 subunit (Animal-Free)

Code Description Price Qty
GFM50AF-2 Mouse IL-27 / p28 subunit (Animal-Free), 2 μg $70.00
GFM50AF-10 Mouse IL-27 / p28 subunit (Animal-Free), 10 μg $180.00
GFM50AF-100 Mouse IL-27 / p28 subunit (Animal-Free), 100 μg $695.00
GFM50AF-1000 Mouse IL-27 / p28 subunit (Animal-Free), 1 mg $5,765.00

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PODS® Growth Factors

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Animal-Free

This product is produced with no animal derived raw products. All processing and handling employs animal free equipment and animal free protocols.

Description

The p28 subunit of interleukin-27 (IL-27), also known as interleukin-30 (IL-30), is a member of the interleukin-12 (IL-12) family of cytokines. p28 is a 28 kDa polypeptide that associates with the Epstein-Barr virus induced gene 3 (EBI-3) to form the IL-27 cytokine heterodimer complex. IL-27 functions as a proinflammatory cytokine that induces immunomodulatory effects in naive CD4+ T cells, mast cells, and monocytes. p28 can also form a complex with Cytokine-Like Factor 1 (CLF), that is secreted by dendritic cells, to regulate Natural Killer (NK) and T cell function.

Activity Assay

Activity to be determined.

AA Sequence

MFPTDPLSLQ ELRREFTVSL YLARKLLSEV QGYVHSFAES RLPGVNLDLL PLGYHLPNVS LTFQAWHHLS DSERLCFLAT TLRPFPAMLG GLGTQGTWTS SEREQLWAMR LDLRDLHRHL RFQVLAAGFK CSKEEEDKEE EEEEEEEEKK LPLGALGGPN QVSSQVSWPQ LLYTYQLLHS LELVLSRAVR DLLLLSLPRR PGSAWDS

Alternative Names

IL-30, P28, IL-27 p28 subunit, interleukin-27, interleukin 27, IL27, IL 27
Product Details
Length 207 aa
Molecular Weight 23.7 kDa
Structure Monomer
Source E. coli
Accession Number Q8K3I6
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium bicarbonate, pH 8.5
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.