Recombinant Mouse MIP-3 β / CCL19

Code Description Price Qty
GFM44-5 Mouse MIP-3 β, 5 μg $65.00
GFM44-20 Mouse MIP-3 β, 20 μg $165.00
GFM44-100 Mouse MIP-3 β, 100 μg $410.00
GFM44-1000 Mouse MIP-3 β, 1 mg $2,950.00

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Description

Macrophage Inflammatory Protein 3 β (MIP-3 β), also known as CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells. MIP-3 β signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation. MIP-3 β also functions during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs. Human MIP-3 β shows activity on mouse cells.

Activity Assay

Activity to be determined.

AA Sequence

GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS

Alternative Names

Macrophage Inflammatory Protein 3 β, MIP-3-β, MIP3, CCL19, SCYA19, ELC, Exodus-3
Product Details
Length 83 aa
Molecular Weight 9.2 kDa
Structure Monomer
Source E. coli
Accession Number Q548P0
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.