Recombinant Rat IL-17F
Achieve Purchasing Synergy
Request a quote at email@example.com for 2 or more vials of any Growth Factor to receive a discount. Discounts range from 5 to 20% according to the size of your order.
PODS® Growth FactorsThe product is currently not available as PODS®, please check back in the future.
DescriptionInterleukin-17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin-6 (IL-6), interleukin-8 (IL-8), and Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endoethelial cell expression of interleukin-2 (IL-2), Monocyte Chemoattractant Protein 1 (MCP-1), and Transforming Growth Factor β 1 (TGF-β1).
Activity AssayRat IL-17F is fully biologically active when compared to standard. The activity is determined by the ability to produce mouse IL-6 by NIH-3T3 cells.
AA SequenceMARRNPKVGL SALQKAGNCP PLEDNSVRVD IRIFNQNQGI SVPRDFQNRS SSPWDYNITR DPDRFPSEIA EAQCRHSGCI NAQGQEDGSM NSVPIQQEIL VLRREPQGCS NSFRLEKMLI KVGCTCVTPI VHHAA
Alternative NamesInterleukin-17F, interleukin 17F, IL17F, IL 17F
|Length||135 / 270 aa|
|Molecular Weight||15.0 / 30.1 kDa|
|Purity||≥95% determined by reducing and non-reducing SDS-PAGE|
|Endotoxin Level||≤1.00 EU/μg as measured by kinetic LAL|
|Formulation||Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)|
|Reconstitution||Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.|
|Stability and Storage||
12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.