Recombinant Rat RANTES / CCL5

Code Description Price Qty
GFR26-5 Recombinant Rat RANTES / CCL5, 5 μg £50.00
GFR26-20 Recombinant Rat RANTES / CCL5, 20 μg £120.00
GFR26-100 Recombinant Rat RANTES / CCL5, 100 μg £310.00
GFR26-100x10 Recombinant Rat RANTES / CCL5, 100 μg x 10 £1,375.00
GFR26-1000 Recombinant Rat RANTES / CCL5, 1 mg £1,375.00
Induced chemotaxis of human THP-1 cells assay for Rat RANTES. Cells that migrated were counted using a luminescent substrate. Migration over basal levels was reported in response to Rat RANTES starting at 10 ng/ml.

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PODS Growth Factors

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Description

Regulated upon activation, normal T cell expressed and secreted (RANTES), also known as CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28. RANTES functions to recruit immune cells to inflammatory sites.

Activity Assay

Rat RANTES is fully biologically active when compared to standard. The activity is determined by the ability to induce chemotaxis of THP-1 cells.

AA Sequence

SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS

Alternative Names

CCL5, TCP228, SIS-delta, SCYA5
Product Details
Length 68 aa
Molecular Weight 7.9 kDa
Structure Monomer
Source E. coli
Accession Number P13501
Purity ≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level ≤1.00 EU/μg as measured by kinetic LAL
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.