Exact Amount™The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.
BIRB796 is a protein kinase inhibitor of p38 MAPK. BIRB796 has high picomolar affinity for p38 MAP kinase and low nanomolar inhibitory activity against TNF-alpha in THP-1 cell culture. The p38 inhibitor BIRB796 binds tightly to ABL(T315I) and inhibits the BMS-354825 and imatinib-resistant ABL(T315I) kinase.
BIRB796 has been used as part of the naive human stem cell (NSHM) medium to create naive state human cells.
Doramapimod, BIRB-796, BIRB 796, 285983-48-4, S1574_Selleck, Kinome_2137, 1kv2, UNII-HO1A8B3YVV, Doramapimod (USAN/INN)
1. Gafni, O., et al. 2013. Nature. 504(7479): 282-286. PMID: 24172903
|Stability and Storage||Stable at -20°C. Keep away from direct sunlight.|