Dasatinib

Code Description Price Qty
SM45-20 Dasatinib, 20 mg £30.00
SM45-100 Dasatinib, 100 mg £85.00
SM45-500 Dasatinib, 500 mg £135.00
SM45-1000 Dasatinib, 1 g £180.00
SM45-5000 Dasatinib, 5 g £535.00
Dasatinib

Activity

Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit.

Effect

Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Alternative Names

BMS-354825, Sprycel

N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide

References

1. Ma, t., et al. 2013. Circ Res. 112(3): 562-574. PMID: 23371904

2. Dos Santos, C., et al. 2013. Blood. 122(11): 1900-1913. PMID: 23896410

Product Details
Formula C22H26CIN7O2S
Molecular Weight 488.01
CAS Number 302962-49-8
Purity >99%
Solubility DMSO
Stability and Storage Stable at -20°C. Keep away from direct sunlight.