GDC-0941
GDC-0941
Exact Amount™
The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.Activity
GDC-0941 is a cell-permeable, selective small molecule that inhibits Class I phosphatidylinositide 3-kinase (PI3K).
Effect
GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.
Alternative Names
Pictilisib
2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidine
References
1. Gibbs, KD. Jr., et al. 2012. Cell Stem Cell. 10(2): 210-217. PMID: 22305570
2. Kanai, R., et al. 2011. Clin Cancer Res. 17(11): 3686-3696. PMID: 21505062
| Product Details | |
|---|---|
| Formula | C23H27N7O3S2 |
| Molecular Weight | 513.64 |
| CAS Number | 957054-30-7 |
| Purity | >99% |
| Solubility | DMSO |
| Stability and Storage | Stable at -20°C. Keep away from direct sunlight. |
