JNJ-10198409
JNJ-10198409
Exact Amount™
The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.Activity
JNJ-10198409 is a potent ATP-competitive inhibitor of Platelet-Derived Growth Factor Receptor Tyrosine Kinase (PDGF-RTK).
Effect
JNJ-10198409 displays potent antiproliferative properties in human tumor cell lines and antiangiogenic activity.
Alternative Names
PDGF Receptor Tyrosine Kinase Inhibitor IV, RWJ-540973, J101
3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine
References
1. Ho, CY., et al. 2005. J Med Chem. 48(26): 8163-8173. PMID: 16366598
2. Danovi, D., et al. 2013. PLoS One. 8(10): e77053. PMID: 24204733
3. Hiram-Bab, S., et al. 2014. J Cell Physiol. 229(6): 743-751. PMID: 24129818
| Product Details | |
|---|---|
| Formula | C18H16FN3O2 |
| Molecular Weight | 325.34 |
| CAS Number | 627518-40-5 |
| Purity | >99% |
| Solubility | DMSO, ethanol |
| Stability and Storage | Stable at -20°C. Keep away from direct sunlight. |
