Code Description Price Qty
SM73-2 PD184352, 2 mg $60.00
SM73-10 PD184352, 10 mg $175.00
SM73-25 PD184352, 25 mg $360.00
SM73-100 PD184352, 100 mg $929.00

Exact Amount™

The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.


PD184352 is a highly selective non-competitive inhibitor of MEK, a kinase upstream in the mitogen-activated protein kinase pathway (MAPK).


PD184352 has anti-cancer properties, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell (ESC) lines.

Alternative Names

PD 184352, PD-184352, CI-1040



1. Mattingly, RR., et al. 2006. J Pharmacol Exp Ther. 316(1): 456-465. PMID: 16239399

2. Zhang, XZ. 2010. Reprod Biomed Online. 21(1): 26-36. PMID: 20462797

3. Pellicano, F., et al. 2011. Leukemia. 25(7): 1159-1167. PMID: 21483442

Product Details
Formula C17H14CIF2IN2O2
Molecular Weight 478.66
CAS Number 212631-79-3
Purity >99%
Solubility DMSO, ethanol
Stability and Storage Stable at -20°C. Keep away from direct sunlight.