Pifithrin μ

Code Description Price Qty
SM29-2.5 Pifithrin μ, 2.5 mg $60.00
SM29-10 Pifithrin μ, 10 mg $175.00
SM29-50 Pifithrin μ, 50 mg $273.00
Pifithrin μ

Exact Amount™

The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.


Pifithrin µ selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. It induces apoptosis and it is cell permeable. Also, inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL.


Pifithrin µ rescues cells from lethal γ-irradiation-induced cell death.

Alternative Names

PFTu, NSC 303580, PIF



1. Strom, E., et al. 2006. Nat Chem Biol. 2: 474-479. PMID: 16862141

2. Xu, X., et al. 2010. Biotechnol Prog. 26: 781-788. PMID: 20014103

3. Steele, A.J., et al. 2009. Blood. 114: 1217-1225. PMID: 19515722

4. Vaseva, A.V., et al. 2009. Cell Cycle. 8: 1711-1719. PMID: 19411846

5. Drakos, E., et al. 2009. Leukemia. 23: 2290-2299. PMID: 19741726

6. Hagn, F., et al. 2010. J. Biol. Chem. 285: 3439-3450. PMID: 19955567

Product Details
Formula C8H7NO2S
Molecular Weight 181.2
CAS Number 64984-31-2
Purity >98%
Solubility DMSO
Stability and Storage Stable at -20°C. Keep away from direct sunlight.