PIK-75 Hydrochloride

Code Description Price Qty
SM76-2 PIK-75 Hydrochloride, 2 mg $60.00
SM76-10 PIK-75 Hydrochloride, 10 mg $175.00
SM76-50 PIK-75 Hydrochloride, 50 mg $376.00
SM76-100 PIK-75 Hydrochloride, 100 mg $650.00
PIK-75 Hydrochloride

Exact Amount™

The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.


PIK-75 is a cell-permeable selective inhibitor of PI 3-kinase p110alpha.


This molecule inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and also activation of mTORC1. It has been studied that PIK-75 significantly reduces leukemia burden and increases the survival of mice engrafted with human acute myeloid leukemia.

Alternative Names

PI3-Kinase α Inhibitor VIII

2-Methyl-5-nitrobenzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide hydrochloride


1. Kingham, E. and Welham, M. 2009. J Cell Sci. 122:2311-2321. PMID: 19509054

2. Yi, YW., et al. 2013. Mol Carcinog. 52(9): 667-675. PMID: 22488590

3. Thomas, D., et al. 2013. Blood. 122(5): 738-748. PMID: 23775716

Product Details
Formula C16H14BrN5O4S.HCl
Molecular Weight 488.74
CAS Number 372196-77-5
Purity >99%
Solubility DMSO
Stability and Storage Stable at -20°C. Keep away from direct sunlight.