Exact Amount™The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.
PTK787 is an inhibitor of VEGFR2/KDR, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. PTK787 also inhibits Flk, c-Kit and PDGFR-β.
PTK787 inhibits VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival. It shows the anti-proliferation effect by inhibiting thymidine incorporation induced by VEGF in HUVECs.
Vatalanib, CGP-79787, ZK222584
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