WH-4-023
WH-4-023
Exact Amount™
The mg quantity of material provided in the smallest pack size for this product is specified on the vial label to two decimal places. This reduces concentration variation and ensures reproducibility in your experiments.Activity
WH-4-023 is a potent and selective inhibitor for Lck and Src kinase. It poorly inhibits p38 alpha and KDR.
Effect
WH-4-023 in combination with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
Alternative Names
Carbamic acid
N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-,2,6-dimethylphenyl ester
References
1. Martin, MW. et al. 2006. J Med Chem. 49(16): 4981-4991. PMID: 16884310
2. Theunissen, TW. et al. 2014. Cell Stem Cell. 15(4): 471-487. PMID: 25090446
| Product Details | |
|---|---|
| Formula | C32H36N6O4 |
| Molecular Weight | 568.67 |
| CAS Number | 837422-57-8 |
| Purity | >99% |
| Solubility | DMSO |
| Stability and Storage | Stable at -20°C. Keep away from direct sunlight. |
