April 2023
Charlie and the cytokine factory
Chocolate directly affects immune system performance. Stripping back the confounding effects of other components, such as sugar, cocoa itself promotes beneficial changes which are reflected in levels of pro- and anti-inflammatory cytokines.
The silence of silk: tolerance of foreign proteins
Immune reactions are a hazard of protein drug development. Why are some foreign proteins such as silk and botulinum toxin (Botox) tolerated when other proteins are not?
New drug technology creates cancer-infiltrating cellular Trojan horses
Cancer drugs struggle to reach a tumour's core. Cambridge researchers develop cellular 'Trojan horse' to deliver cancer drugs more effectively.
Exosomes and metabolism: a target for therapy?
As ubiquitous messengers, exosomes play a role in how our bodies manage energy. From adipocytes to the gut microbiome, new insights into how exosomes modulate human metabolism might be providing a glimpse into the future of metabolic disease treatment.