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Bacteria in metastases: The microbiome of cancer

Bacteria in metastases: The microbiome of cancer

Within our bodies, microbes have developed an essential, commensal role and are found in many niches. A comprehensive study, recently published in Cell, provides a fascinating insight into the role of microbes in cancer and how they can modulate prognosis and responses to treatment.

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What are the biggest proteins?

What are the biggest proteins?

For proteins, size does matter. The size of proteins is related to their function. Most of the really big proteins are found in muscles. Muscle cells are specialized for contraction and force generation, processes that rely on the precise organization and interaction of several large protein complexes.

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Cancers with the best, worst and most improved prognosis

Cancers with the best, worst and most improved prognosis

Over the last 25 years, the survival statistics for cancer patients have improved. Changes in lifestyle (e.g. smoking), earlier detection and better therapies have all contributed. Here, we look at which cancers have the best, worst and most improved survival rates.

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A beginners guide to ADME Tox

A beginners guide to ADME Tox

Understanding the way a drug interacts with our body, and the risks that this poses, is a critical part of drug development. In this article, we describe the basic aspects of ADME Tox, with specific examples.

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Harnessing Macrophages to treat disease

Harnessing Macrophages to treat disease

These versatile cells, known for their multiple roles in engulfing and digesting cellular debris, pathogens, and attacking cancer cells as well as rebuilding damaged tissue, are at the center of a new wave of treatments. Companies around the world are exploiting the unique properties of macrophages to develop groundbreaking therapies for a wide range of diseases.

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The abscopal effect: unexpected cancer therapeutic dividends

The abscopal effect: unexpected cancer therapeutic dividends

Cancer treatment has long been a battlefield of precision, targeting tumors with treatments like surgery, chemotherapy, and radiation. However, a rare and fascinating phenomenon known as the abscopal effect has intrigued oncologists and researchers, offering a glimpse into the hidden power of the body to fight cancer beyond the direct line of treatment.

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Engineering nature: The world of synthetic biology

Engineering nature: The world of synthetic biology

In recent years, the field of synthetic biology has emerged as a revolutionary branch of science, blending engineering principles with biology to reshape the way we understand and interact with living organisms. This groundbreaking discipline combines the power of genetics, biochemistry, and computer science to design, construct, and optimize new biological systems. With its vast potential to address critical global challenges, synthetic biology has garnered immense attention from researchers, innovators, regulators and policymakers alike.

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