December 2023

Top 10 cytokines and chemokines for immunotherapy of cancer

Top 10 cytokines and chemokines for immunotherapy of cancer

The efficacy of chemokines and cytokines can vary depending on the type of cancer and the individual immune response of each pateint. However, some cytokines and chemokines stand out for their promise in cancer immunotherapy based on their roles in modulating the immune response. The following is a brief summary of some of these. They are listed in rough order of their relative importance.

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Vestibular neuron breakthrough enabled by PeptiGel and PODS

Vestibular neuron breakthrough enabled by PeptiGel and PODS

In a technology breakthrough utilizing both PODS and PeptiGel, researchers at the University of California in San Diego have used a microfluidic approach to accurately generate vestibular nerve cells to improve electrical vestibular stimulation (EVS) prosthetic outcomes.

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Burst release: what is it and how can it be addressed?

Burst release: what is it and how can it be addressed?

Depot formulations combine an active substance with an excipient to provide controlled release of the active substance over a sustained period of time. Burst release is uncontrolled release which occurs when a large proportion of the active substance in a depot formulation is rapidly released in the first few minutes and hours. Following burst release, a more constant, slow release is then achieved.

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