The activity of a cell is organised by a range of structures, from large organelles to small protein complexes. Amongst these, each cell contains around 100,000 ellular vaults, or simply vaults. These are enigmatic mid-size symmetrical cellular ribonucleoprotein structures that play a role in the storage and transport of molecules within cells.
In biomanufacturing, growth factors and cytokines are crucial for the cultivation and maintenance of cell cultures, particularly in the production of therapeutic proteins, vaccines, and other biologics. Just a few growth factors are widely used.
Animal cells grown in a cell culture conditions play a pivotal role in both research and biomanufacturing, serving as essential tools for scientific discovery and the production of complex biological products. Their use spans a wide range of applications, from basic biological research to the production of vaccines, therapeutic proteins and food.
Research relies on standards. For extracellular vescicles, a common language has been developed that allows a shared understanding and interpretation of data across labs.
Karyotyping remains an important assay when working with any animal cell. Here we discuss the benefits and limitations.
Tropical climates yield high levels of biodiversity. So perhaps it is not surprising that the natural resources of many tropical islands have made significant contributions to the development of some very big (and some not so big) name drugs.
Using bioreactors to generate seafood or meat is horrific or exciting, depending on your point of view. As with genetically modified food, attitudes differ markedly between countries.
Chemokines are promising modalities in the treatment of disease. These small signaling proteins, primarily known for their role in directing the movement of immune cells, are now being explored for their therapeutic potential in a range of conditions, from cancer to chronic inflammatory diseases.
Creating a chemokine or growth factor concentration gradient is a crucial lab technique for studying cell migration, particularly in neuroscience, immunology and cancer research. Sustained release growth factors can simplify chemotaxis studies.
RADA16, the pioneer in the field of self-assembling peptide hydrogels, is inflexible (figuratively at least) and can be difficult to use. PeptiGel is winning out with clever refinement, bespoke formulation and a ready-to-use format.
